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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCRS1
All Species:
40.91
Human Site:
S222
Identified Species:
75
UniProt:
Q96EZ8
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96EZ8
NP_001012300.1
462
51803
S222
Q
L
L
S
K
V
G
S
T
S
Q
P
T
L
E
Chimpanzee
Pan troglodytes
XP_509047
513
57528
S273
Q
L
L
S
K
V
G
S
T
S
Q
P
T
L
E
Rhesus Macaque
Macaca mulatta
XP_001109790
462
51406
S222
Q
L
L
S
K
V
G
S
T
S
Q
P
T
L
E
Dog
Lupus familis
XP_850537
462
51831
S222
Q
L
L
S
K
V
G
S
T
S
Q
P
T
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q99L90
462
51674
S222
Q
L
L
S
K
V
G
S
S
S
Q
P
T
L
E
Rat
Rattus norvegicus
NP_001013124
462
51804
S222
Q
L
L
S
K
V
G
S
T
S
Q
P
T
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512056
254
28409
S59
H
P
D
A
F
Y
L
S
R
T
P
K
A
L
Q
Chicken
Gallus gallus
XP_001232507
447
50517
F227
L
H
K
H
P
D
V
F
Y
P
S
R
T
A
K
Frog
Xenopus laevis
NP_001080873
453
50959
S213
Q
L
L
S
I
V
S
S
A
S
Q
P
T
L
D
Zebra Danio
Brachydanio rerio
NP_998438
472
53117
S232
A
L
L
A
K
I
T
S
N
S
Q
P
K
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647852
578
63519
S334
D
L
L
G
T
I
K
S
S
E
Q
P
K
L
E
Honey Bee
Apis mellifera
XP_624688
469
53205
S231
D
L
L
G
T
I
K
S
T
S
Q
P
T
V
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797067
874
96141
S636
K
L
V
G
T
V
T
S
S
S
Q
P
T
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90
94.1
99.1
N.A.
98.2
98.4
N.A.
45
85.2
82
75.4
N.A.
44.6
51.5
N.A.
33.9
Protein Similarity:
100
90
94.5
99.3
N.A.
98.4
98.6
N.A.
48
90.9
90
86.2
N.A.
59
69.5
N.A.
43.1
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
13.3
6.6
73.3
53.3
N.A.
46.6
60
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
33.3
13.3
80
73.3
N.A.
60
73.3
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
16
0
0
0
0
8
0
0
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
8
0
0
8
0
0
0
0
0
0
0
0
24
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
62
% E
% Phe:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
24
0
0
47
0
0
0
0
0
0
0
0
% G
% His:
8
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
24
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
8
0
54
0
16
0
0
0
0
8
16
0
8
% K
% Leu:
8
85
77
0
0
0
8
0
0
0
0
0
0
77
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
8
0
0
0
0
8
8
85
0
0
0
% P
% Gln:
54
0
0
0
0
0
0
0
0
0
85
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% R
% Ser:
0
0
0
54
0
0
8
93
24
77
8
0
0
0
0
% S
% Thr:
0
0
0
0
24
0
16
0
47
8
0
0
77
0
0
% T
% Val:
0
0
8
0
0
62
8
0
0
0
0
0
0
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _